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Exosome Research Direction
  • Tumor
  • Stem cell
  • Cardiovascular
  • Immunity
  • Nervous system
  • Methods and omics
  • Diagnosis
  • Targeted drug delivery
  • Secretory mechanism
Tumor
Tumor
Exosomes have a wide range of applications in tumor detection, tumor therapy and prognosis.
TumorRelated articles include14a piece of writing
Stem cells
Stem cell
Stem cell exosomes can be used as a novel cell therapy with a wide range of biological functions and medical applications.
Stem cellRelated articles include10a piece of writing
Cardiovascular
Cardiovascular
The therapeutic potential of exosomes for cell-free treatment of cardiovascular disease applies to a wide range of diseases, including myocardial infarction, atherosclerosis, and dilated cardiomyopathy.
CardiovascularRelated articles include9a piece of writing
Immunity
Immunity
Exosomes perform a variety of biological functions in the immune system.
ImmunityRelated articles include8a piece of writing
Nervous system
Nervous system
Exosomes can cross the blood-brain barrier, and have great potential for use in many neurological disorders and other areas.
Nervous systemRelated articles include3a piece of writing
Methodology and omics
Methods and omics
iversification studies of exosomes from different sources.
Methods and omicsRelated articles include7a piece of writing
Diagnosis
Diagnosis
Exosomes offer a novel approach to disease diagnosis.
DiagnosisRelated articles include10a piece of writing
Targeted drug delivery
Targeted drug delivery
Exosomes can be engineered to confer excellent targeting properties.
Targeted drug deliveryRelated articles include10a piece of writing
Secretory mechanism
Secretory mechanism
Exosomes are a key mediator of intercellular communication and play an important role in a variety of physiological and pathological processes.
Secretory mechanismRelated articles include10a piece of writing
Global exosome company
  • Exosomics

    總部位于意大利錫耶納，正在開發(fā)基于外泌體的早期癌癥篩查和分子診斷測試。公司提供檢測外泌體中 RNA 和 DNA 突變的試劑盒和參考標準。這些試劑盒用于癌癥篩查和液體活檢，適用于研究使用和臨床診斷。與 Lonza 公司有戰(zhàn)略合作伙伴關系。Exosomics在從復雜生物流體中分離和選擇性富集腫瘤來源的細胞外囊泡（EV）/外泌體方面擁有長期的專業(yè)知識和獨特的知識產(chǎn)權。使命是開發(fā)和商業(yè)化基于循環(huán)細胞外囊泡和外泌體的分析的新一代癌癥篩查和液體活檢的測試。公司為癌癥篩查和液體活檢提供廣泛的專用試劑和試劑盒，適用于研究和臨床診斷。渠道涵蓋EV /外泌體樣品流的所有步驟，從預分析方法到實物分析。Exosomics預創(chuàng)一個靠簡單抽血就能進行癌癥診斷和監(jiān)測的世界，使醫(yī)生能夠為每位患者選擇最佳治療方案。
     

  • Mursla

    2019年3月，Pierre Arsène在英國成立了Mursla公司，致力于利用外泌體生物學提供下一代多組學液體活檢解決方案。經(jīng)過3年多的發(fā)展，Mursla目前擁有多名液體活檢領域研究經(jīng)驗豐富的顧問和一支優(yōu)秀的研發(fā)團隊。

    在外泌體制備方面，Mursla開發(fā)了一種通過結合密度緩沖和尺寸排除色譜(SEC)從血漿中分離出外泌體的新方法，得到的外泌體中的脂蛋白顆粒污染最小。同時，可提取血液中不同的外泌體亞群。

    在外泌體分析方面，Mursla合成了一個名叫ExoPheno™的技術平臺工具，該平臺通過機器學習集成了干、濕實驗室分析，可以檢測、分析血液中組織特異性外泌體的多組學“貨物”，用于各種生物醫(yī)學應用。

  • Nanostics

    Nanostics是一家專注于開發(fā)及商業(yè)化新型和非侵入性診斷測試的公司，其開發(fā)的新型液體活檢平臺，核心技術是將高靈敏度的細胞外囊泡（EV）/外泌體檢測平臺——英國Apogee納米流式分析儀與先進的機器學習算法相結合，通過簡單的血液收集即可進行檢測診斷疾病，適用于各種癌癥和其他疾病。目前在診斷膀胱癌和前列腺癌領域的成功必將為其他疾病的診斷和篩查帶來意義非凡的技術方向和實踐平臺。核心技術ClarityDX®技術可用于疾病預測。鑒定病變細胞/組織表達的生物標志物 ，確定是否需要治療 ，預測治療反應和耐藥性 ，疾病分期 ，識別疾病復發(fā)。

  • INOVIQ

    INOVIQ公司匯集了一系列基于外泌體的產(chǎn)品，可用于癌癥和其他嚴重疾病的早期檢測、診斷、預后和監(jiān)測。具體來說，EXO-NET®可以“快速、準確、高效地從任何液體活檢樣本中捕獲并分離外泌體”。該技術可與現(xiàn)有的自動化檢測系統(tǒng)兼容，非常適合大批量臨床樣本的檢測。

Well-known Exosome Experts
  • James E. Rothman

    Born 1950, USA Yale University, New Haven

  • Randy W. Schekman

    Born 1948, USA University of California, Berkeley

  • Thomas C. Südhof

    Born 1955,Germany Stanford University, Palo Alto

  • Raghu Kalluri

    Professor, Department of Cancer Biology, The University of Texas MD Anderson Cancer Center

  • Aikawa, Elena

    Professor of Medicine, Harvard Medical School

  • Xandra Breakefield

    Professor of Neurology,?Harvard Medical School

  • David Lyden

    Laboratory of Experimental Cancer Research, Department of Radiation Oncology and Experimental Cancer Research, Ghent University Hospital, Ghent, Belgium

  • María Yá?ez-Mó

    Laboratory of Experimental Cancer Research, Department of Radiation Oncology and Experimental Cancer Research, Ghent University Hospital, Ghent, Belgium

  • Olivier De Wever

    Laboratory of Experimental Cancer Research, Department of Radiation Oncology and Experimental Cancer Research, Ghent University Hospital, Ghent, Belgium

  • Peter Kierulf

    Laboratory of Experimental Cancer Research, Department of Radiation Oncology and Experimental Cancer Research, Ghent University Hospital, Ghent, Belgium

Exosome Related Informations
  • Global
  • National